Big Data in Healthcare Made Simple: Where It Stands Today and Where It’s Going

Barriers Exist for Using Big Data in Healthcare Today

Several challenges with big data have yet to be addressed in the current big data distributions. Two roadblocks to the general use of big data in healthcare are the technical expertise required to use it and a lack of robust, integrated security surrounding it.

Expertise

The value for big data in healthcare today is largely limited to research because using big data requires a very specialized skill set. Hospital IT experts familiar with SQL programming languages and traditional relational databases aren’t prepared for the steep learning curve and other complexities surrounding big data.

In fact, most organizations need data scientists to manipulate and get data out of a big data environment. These are usually Ph.D.-level thinkers with significant expertise—and typically, they’re not just floating around an average health system. These experts are hard to come by and expensive, and only research institutions usually have access to them. Data scientists are in huge demand across industries like banking and internet companies with deep pockets.

The good news is thanks to changes with the tooling, people with less-specialized skillsets will be able to easily work with big data in the future. Big data is coming to embrace SQL as the lingua franca for querying. And when this happens, it will become useful in a health system setting.

Microsoft’s Polybase is an example of a query tool that enables users to query both Hadoop Distributed File System (HDFS) systems and SQL relational databases using an extended SQL syntax. Other tools such as Impala, enable the use of SQL over a Hadoop database. These types of tools will bring big data to a larger group of users.

Security

In healthcare, HIPAA compliance is non-negotiable. Nothing is more important than the privacy and security of patient data. But, frankly, there aren’t many good, integrated ways to manage security in big data. Although security is coming along, it has been an afterthought up to this point. And for good reason. If a hospital only has to grant access to a couple of data scientists, it really doesn’t have too much to worry about. But when opening up access to a large, diverse group of users, security cannot be an after thought.

Healthcare organizations can take some steps today to ensure better security of big data. Big data runs on open source technology with inconsistent security technology. To avoid big problems, organizations should be selective about big data vendors and avoid assuming that any big data distribution they select will be secure.

The best option for healthcare organizations looking to implement big data is to purchase a well-supported, commercial distribution rather than starting with a raw Apache distribution. Another option is to select a cloud-based solution like Azure HDInsight to get started quickly. An example of a company with a well supported, secure distribution is Cloudera. This company has created a Payment Card Industry (PCI) compliant Hadoop environment supporting authentication, authorization, data protection, and auditing. Surely other commercial distributions are working hard to add more sophisticated security that will be well-suited for HIPAA compliance and other security requirements unique to the healthcare industry.

Big Data Differs from the Databases Currently Used in Healthcare

Big data differs from a typical relational database. This is obvious to a CIO or an IT director, but a brief explanation of how the two systems differ will show why big data is currently a work in progress—yet still holds so much potential.

Big Data Has Minimal Structure

The biggest difference between big data and relational databases is that big data doesn’t have the traditional table-and-column structure that relational databases have. In classic relational databases, a schema for the data is required (for example, demographic data is housed in one table joined to other tables by a shared identifier like a patient identifier). Every piece of data exists in its well-defined place. In contrast, big data has hardly any structure at all. Data is extracted from source systems in its raw form stored in a massive, somewhat chaotic distributed file system. The Hadoop Distributed File System (HDFS) stores data across multiple data nodes in a simple hierarchical form of directories of files. Conventionally, data is stored in 64MB chunks (files) in the data nodes with a high degree of compression.

Big Data Is Raw Data

By convention, big data is typically not transformed in any way. Little or no “cleansing” is done and generally, no business rules are applied. Some people refer to this raw data in terms of the “Sushi Principle” (i.e. data is best when it’s raw, fresh, and ready to consume). Interestingly, the Health Catalyst Late-Binding™ Data Warehouse follows the same principles. This approach doesn’t transform data, apply business rules, or bind the data semantically until the last responsible moment–in other words, bind as close to the application layer as possible.

Big Data Is Less Expensive

Due to its unstructured nature and open source roots, big data is much less expensive to own and operate than a traditional relational database. A Hadoop cluster is built from inexpensive, commodity hardware, and it typically runs on traditional disk drives in a direct-attached (DAS) configuration rather than an expensive storage area network (SAN). Most relational database engines are proprietary software and require expensive licensing and maintenance agreements. Relational databases also require significant, specialized resources to design, administer, and maintain. In contrast, big data doesn’t need a lot of design work and is fairly simple to maintain. A lot of storage redundancy allows for more tolerable hardware failures. Hadoop clusters are designed to simplify rebuilding of failed nodes.

Big Data Has No Roadmap

The lack of pre-defined structure means a big data environment is cheaper and simpler to create. So what’s the catch? The difficulty with big data is that it’s not trivial to find needed data within that massive, unstructured data store. A structured relational database essentially comes with a roadmap—an outline of where each piece of data exists. On the big data side, there are no traditional schemas, and therefore not much guidance. With a relational database, a simple, structured query language (i.e. SQL) pulls the needed data using a sophisticated query engine optimized for finding data.

With big data, the query languages are much more complicated. A sophisticated data user—such as a data scientist—is needed to find the subset of data required for applications. Creating the required MapReduce algorithms for querying big data instances isn’t for the faint of heart. Fortunately, that’s changing at a fairly rapid pace with tools like SparkSQL and other query tools that leverage conventional SQL for querying. Big data query engines can now convert SQL queries into MapReduce jobs while others like the aforementioned Microsoft PolyBase can join queries from a traditional relational database and Hadoop then return a single result set.

In short, big data is cheap but more difficult to use. Relational databases are expensive but very usable. The maturity level of big data technology is low–after all the big data journey only began a few short years ago. So, as the tooling and security catches up with its potential, health systems will be able to do exciting things with it.

It’s Coming: Big Data Will Be Important in Healthcare

When healthcare organizations envision the future of big data, they often think of using it for analyzing text-based notes. Current analytics technologies for the most part make use of discrete data and struggle to capitalize on all of the valuable clinical information captured in physicians’ and nurses’ notes. Big data indexing techniques, and some of the new work finding information in textual fields, could indeed add real value to healthcare analytics in the future.

Big Data and the Internet of Things

Big data will really become valuable to healthcare in what’s known as the internet of things (IoT). SAS describes the IoT as:

The Internet of Things is a growing network of everyday objects from industrial machines to consumer goods that can share information and complete tasks while you are busy with other activities, like work, sleep, or exercise. Soon, our cars, our homes, our major appliances, and even our city streets will be connected to the Internet–creating this network of objects that is called the Internet of Things, or IoT for short. Made up of millions of sensors and devices that generate incessant streams of data, the IoT can be used to improve our lives and our businesses in many ways.

The analyst firm Gartner projects that by 2020 there will be more than 25 billion connected devices in the IoT. For healthcare, any device that generates data about a person’s health and sends that data into the cloud will be part of this IoT. Wearables are perhaps the most familiar example of such a device. Many people now can wear a fitness device that tracks how many steps they’ve taken, their heartrate, their weight, and how it’s all trending. Apps are available on smart phones that track how often and how intensely a user exercises. There are also medical devices that can also send data into the cloud: blood pressure monitors, pulse oximeters, glucose monitors, and much, much more.

Big Data and Care Management

ACOs focus on managed care and want to keep people at home and out of the hospital. Sensors and wearables will collect health data on patients in their homes and push all of that data into the cloud. Electronic scales, BP monitors, SpO2 sensors, proximity sensors like iBeacon, and soon-to-be-invented sensors will blast data from millions of patients continually. Healthcare institutions and care managers, using sophisticated tools, will monitor this massive data stream and the IoT to keep their patients healthy.

And all of this disparate sensor data will come into healthcare organizations at an unprecedented volume and velocity. In a healthcare future predicated on keeping people out of the hospital, a health system’s ability to manage all this data will be crucial. These volumes of data are best managed as streams coming into a big data cluster. As the data streams in, organizations will need to be able to identify any potential health issues and alert a care manager to intervene. For example, if a patient’s blood pressure spikes, the system will send an alert in real time to a care manager who can then interact with the patient to get his blood pressure back into a healthy range.Big data is the only hope for managing the volume, velocity, and variety of this sensor data.

The Fun Stuff: Using Big Data for Predictive Analytics, Prescriptive Analytics, and Genomics

Real-time alerting is just one important future use of big data. Another is predictive analytics. The use cases for predictive analytics in healthcare have been limited up to the present because we simply haven’t had enough data to work with. Big data can help fill that gap.

One example of data that can play a role in predictive analytics is socioeconomic data. Socioeconomic factors influence patient health in significant ways. Socioeconomic data might show that people in a certain zip code are unlikely to have a car. There is a good chance, therefore, that a patient in that zip code who has just been discharged from the hospital will have difficulty making it to a follow-up appointment at a distant physician’s office. (Health systems have, in fact, found that it is cheaper to send a taxi to pick a patient up for an appointment than it is for her to miss the appointment and be readmitted to the hospital.)

This and similar data can help organizations predict missed appointments, noncompliance with medications, and more. That is just a small example of how big data can fuel predictive analytics. The possibilities are endless.

Patient Flight Paths and Prescriptive Analytics

Another use for predictive analytics is predicting the “flight path” of a patient. Leveraging historical data from other patients with similar conditions, predictive algorithms can be created using programming languages such as R and big data machine learning libraries to faithfully predict the trajectory of a patient over time.Once we can accurately predict patient trajectories, we can shift to the Holy Grail–Prescriptive Analytics. Intervening to interrupt the patient’s trajectory and set him on the proper course will become a reality very soon. Big data is well suited for these futuristic use cases.

Genomic Sequencing and Big Data

As someone who’s spent many years working on the Human Genome project, I am personally very excited about the increasing use of genomic data in patient treatment. The cost of sequencing an individual’s full genome has plunged in recent years. Sequencing, once an art, will soon become commonplace and eventually become a commodity lab test. Genomic sequences are huge files and the analysis of genomes generates even more data. Again, big data serves this use case well. Loading a genetic sequence into a relational database would require a huge Character Large Object (CLOB) or a separate storage just to manage the sequence. With big data, just toss it in the Hadoop cluster, and it’s ready for analysis.

The Future of Healthcare Data Warehousing and the Transition to Big Data

I’ve talked about the present limitations for big data in healthcare and the truly fascinating future possibilities that big data enables. An important question to address at this point is, of course, this: What should a health system do in the meantime? Today, health systems’ need for data-driven quality and cost improvement is urgent. Healthcare organizations cannot afford to wait for big data technology to mature before diving into analytics. The important factor will be choosing a data warehousing solution that can easily adapt to the future of big data.

A Late-Binding™ enterprise data warehouse (EDW) architecture is ideal for making the transition from relational databases to unstructured big data. As stated earlier, the late-binding approach is, in fact, very similar to the big data approach. In a Late-Binding EDW like Health Catalyst’s, data from source systems (EHRs, financial systems, etc.) are placed into source marts. In this process—as in big data—it is best practice to keep the data as raw as possible, relying on the natural data models of the source systems. As much as possible, late-binding methods minimize remodeling data in the source marts until the analytic use case requires it. The data remains in its raw state until someone needs it. At that point, analysts package the data into a separate data mart and apply meaning and semantic context so that effective analysis can occur. Because this approach is so similar to big data, it is a natural transition to replace the source-mart layer of the EDW architecture with a big data cluster.

Real World Example Healthcare’s Transition to Big Data

In conclusion, here is a brief example of how the transition from relational databases to big data is happening in the real world. We, at Health Catalyst, are working with one of our large health system clients and Microsoft to create a massively parallel data warehouse in a Microsoft APS Appliance that also includes a Horton works Hadoop Cluster. This means we can run a traditional relational database and a big data cluster in parallel. We can query both data stores simultaneously, which significantly improves our data processing power. Together, we are beginning to experiment with big data in important ways, such as performing natural language processing (NLP) with physician notes, predictive analytics, and other use cases.

The progression from today’s symmetric multiprocessing (SMP) relational databases to massively parallel processing (MPP) databases to big data in healthcare is underway.

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(Source: http://bit.ly/2v5Wk8A)